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Review
. 2009 Mar;256(3):320-32.
doi: 10.1007/s00415-009-0144-7. Epub 2009 Feb 17.

Acquired hepatocerebral degeneration

Joseph Ferrara  1 , Joseph Jankovic
Affiliations
Review

Acquired hepatocerebral degeneration

Joseph Ferrara et al. J Neurol. 2009 Mar.

Abstract

Cirrhosis and its co-morbidities may cause a variety of neurological complications, the most common being bouts of toxic metabolic encephalopathy. A proportion of patients with chronic liver disease develop acquired hepatocerebral degeneration (AHD), a chronic progressive neurological syndrome characterized by parkinsonism, ataxia and other movement disorders. This article reviews the clinical spectrum, pathophysiology, neuroimaging features and differential diagnosis of AHD along with emerging treatment options.

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