Comment on

• Incomplete restoration of Mpl expression in the mpl-/- mouse produces partial correction of the stem cell-repopulating defect and paradoxical thrombocytosis.

  Lannutti BJ, Epp A, Roy J, Chen J, Josephson NC. Lannutti BJ, et al. Blood. 2009 Feb 19;113(8):1778-85. doi: 10.1182/blood-2007-11-124859. Epub 2008 Sep 16. Blood. 2009. PMID: 18796624 Free PMC article.
• Pronounced thrombocytosis in transgenic mice expressing reduced levels of Mpl in platelets and terminally differentiated megakaryocytes.

  Tiedt R, Coers J, Ziegler S, Wiestner A, Hao-Shen H, Bornmann C, Schenkel J, Karakhanova S, de Sauvage FJ, Jackson CW, Skoda RC. Tiedt R, et al. Blood. 2009 Feb 19;113(8):1768-77. doi: 10.1182/blood-2008-03-146084. Epub 2008 Oct 9. Blood. 2009. PMID: 18845793