Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2009 Mar;60(3):496-7.
doi: 10.1016/j.jaad.2008.09.007.

Bortezomib-induced histiocytoid Sweet syndrome

Jenny E Murase  1 , Jashin J Wu, Ivan Theate, Gary W Cole, Ronald J Barr, Senait W Dyson
Affiliations
Case Reports

Bortezomib-induced histiocytoid Sweet syndrome

Jenny E Murase et al. J Am Acad Dermatol. 2009 Mar.

Abstract

Bortezomib, a proteasome inhibitor approved for the treatment of multiple myeloma, has been reported to be associated with Sweet syndrome. However, careful review of the histopathology of the first reported case and our case revealed similar histologic and immunohistochemical findings (a mononuclear dermal infiltrate) and not the usual neutrophilic infiltrate of Sweet syndrome. We suggest that the dermatitis induced by bortezomib is best classified as "histiocytoid Sweet syndrome."

PubMed Disclaimer

Publication types