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Review
. 2009 Mar;11(3):195-210.
doi: 10.1016/j.jfms.2009.01.004.

Therapies for feline chronic kidney disease. What is the evidence?

Philip Roudebush  1 , David J Polzin, Sheri J Ross, Todd L Towell, Larry G Adams, S Dru Forrester
Affiliations
Review

Therapies for feline chronic kidney disease. What is the evidence?

Philip Roudebush et al. J Feline Med Surg. 2009 Mar.

Abstract

Practical relevance Successful treatment and prevention of kidney disease in pet animals requires a multidimensional approach to identify and eliminate causes or exacerbating factors, provide professional examination and care on a regular basis, and plan and implement a comprehensive treatment program when necessary.

Evidence base Over the years, many therapeutic and preventive interventions have been developed or advocated for chronic kidney disease (CKD), but evidence of efficacy or effectiveness is often lacking or highly variable. Accordingly, the main objective of this systematic review was to identify and critically appraise the evidence supporting various approaches to managing feline CKD; namely, fluid therapy, calcitrioi therapy, antihypertensive therapy, ACE inhibitor therapy, erythropoietic hormone replacement therapy, potassium supplementation, antioxidant supplementation, alkalinization therapy, dietary phosphorus restriction and intestinal phosphate binders, therapeutic renal foods, assisted feeding, dialysis and renal transplantation.

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Figures

Fig 1
Fig 1
Retinal Image from a 10-year-old spayed female domestic shorthair cat with acute blindness. Chronic kidney disease and hypertension were diagnosed
Fig 2
Fig 2
Lateral (a) and ventrodorsal (b) abdominal radiographs of a cat with chronic kidney disease and bilateral renomegaly. Lymphoma, polycystic kidney disease and feline infectious peritonitis were considered as potential causes. Diagnostic evaluation confirmed the presence of lymphoma
Fig 3
Fig 3
Kidneys from a cat that died as a result of acute progression of chronic kidney disease. Necropsy confirmed the presence of renal hypoplasia (small kidney) and renal hypertrophy (larger kidney)
None
See this image and copyright information in PMC

References

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