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. 2009 Mar;133(3):257-62.
doi: 10.1085/jgp.200810138.

Polymodal ligand sensitivity of TRPA1 and its modes of interactions

Sangsu Bang  1 , Sun Wook Hwang
Affiliations

Polymodal ligand sensitivity of TRPA1 and its modes of interactions

Sangsu Bang et al. J Gen Physiol. 2009 Mar.
No abstract available

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Figures

Figure 1.
Figure 1.
Electrophilic TRPA1 ligands and the cysteine residues in TRPA1, which covalently bind to the ligands, leading to channel activation. Exogenous chemicals are listed at the top, and physiological ligands are listed at the bottom. The critical cysteine residues are indicated by circles (red, from mouse TRPA1; blue, from human TRPA1; purple, from both). EF, the location of the Ca2+-binding EF-hand domain.
See this image and copyright information in PMC

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