Kinase domain mutations in cancer: implications for small molecule drug design strategies
- PMID: 19239229
- DOI: 10.1021/jm8010542
Kinase domain mutations in cancer: implications for small molecule drug design strategies
Similar articles
-
Targeting cancer with small-molecular-weight kinase inhibitors.Methods Mol Biol. 2012;795:1-34. doi: 10.1007/978-1-61779-337-0_1. Methods Mol Biol. 2012. PMID: 21960212 Review.
-
Deal watch: Bristol-Myers Squibb and Exelixis collaborate on kinase inhibitors.Nat Rev Drug Discov. 2009 Feb;8(2):98. doi: 10.1038/nrd2822. Nat Rev Drug Discov. 2009. PMID: 19180098 No abstract available.
-
Advancing the kinase field: new targets and second generation inhibitors.J Med Chem. 2015 Jan 8;58(1):1. doi: 10.1021/jm5018708. Epub 2014 Dec 9. J Med Chem. 2015. PMID: 25490234 No abstract available.
-
Issues and progress with protein kinase inhibitors for cancer treatment.Nat Rev Drug Discov. 2003 Apr;2(4):296-313. doi: 10.1038/nrd1066. Nat Rev Drug Discov. 2003. PMID: 12669029 Review.
-
RAS: target for cancer therapy.Cancer Invest. 2008 Nov;26(9):948-55. doi: 10.1080/07357900802087275. Cancer Invest. 2008. PMID: 18798058 Review.
Cited by
-
General Method of Synthesis of 5-(Het)arylamino-1,2,3-triazoles via Buchwald-Hartwig Reaction of 5-Amino- or 5-Halo-1,2,3-triazoles.Molecules. 2022 Mar 20;27(6):1999. doi: 10.3390/molecules27061999. Molecules. 2022. PMID: 35335361 Free PMC article.
-
Synthesis of highly substituted 2,3-dihydropyrimido[4,5-d]pyrimidin-4(1H)-ones from 4,6-dichloro-5-formylpyrimidine, amines and aldehydes.Mol Divers. 2011 Nov;15(4):839-47. doi: 10.1007/s11030-011-9314-5. Epub 2011 Apr 21. Mol Divers. 2011. PMID: 21509500
-
c-Src binds to the cancer drug Ruxolitinib with an active conformation.PLoS One. 2014 Sep 8;9(9):e106225. doi: 10.1371/journal.pone.0106225. eCollection 2014. PLoS One. 2014. PMID: 25197973 Free PMC article.
-
Cu(ii)-catalyzed C-N coupling of 2-aminobenzothiazoles with boronic acids at room temperature.RSC Adv. 2023 Jun 8;13(25):17188-17193. doi: 10.1039/d3ra02979d. eCollection 2023 Jun 5. RSC Adv. 2023. PMID: 37304782 Free PMC article.
-
A computational workflow for the design of irreversible inhibitors of protein kinases.J Comput Aided Mol Des. 2010 Mar;24(3):183-94. doi: 10.1007/s10822-010-9324-x. Epub 2010 Mar 21. J Comput Aided Mol Des. 2010. PMID: 20306284
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Chemical Information