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. 2009:492:381-93.
doi: 10.1007/978-1-59745-493-3_23.

Mass spectrometric characterization of neuropeptides

Stephanie S Cape  1 , James A Dowell, Lingjun Li
Affiliations

Mass spectrometric characterization of neuropeptides

Stephanie S Cape et al. Methods Mol Biol. 2009.

Abstract

Because of their great biological significance, neuropeptides are the subject of intensive research. Mass spectrometry (MS) is a highly informative and sensitive method used for detecting and characterizing these compounds. Successful MS analysis of neuropeptides is dependent on careful sample preparation. Herein, we present two common sample preparation strategies: direct tissue analysis and pooled tissue extraction coupled with fractionation.

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