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. 2009 Mar 25;131(11):3796-7.
doi: 10.1021/ja8054595.

Synthesis and reactivity of a mono-sigma-aryl palladium(IV) fluoride complex

Nicholas D Ball  1 , Melanie S Sanford
Affiliations

Synthesis and reactivity of a mono-sigma-aryl palladium(IV) fluoride complex

Nicholas D Ball et al. J Am Chem Soc. .

Abstract

This communication describes the rational design and synthesis of the remarkably stable Pd(IV) monoaryl fluoride complex (t-Bu-bpy)Pd(IV)(p-FC(6)H(4))(F)(2)(FHF) (t-Bu-bpy = 4,4'-di-tert-butyl-2,2'-bipyridine). This and related complexes undergo Ar-F bond formation in the presence of "F(+)" sources. This work serves as a foundation for the development of Pd(II/IV)-catalyzed coupling reactions to form aryl fluorides.

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References

    1. Thayer AM. Chem. Eng. News. 2006;84:15.
    1. Kirk KL. Org. Proc. Res. Dev. 2008;12:305. and references therein.
    2. Banks RE, Tatlow JC, Smart BE. Organofluorine Chemistry: Principles and Commercial Applications. New York: Plenum Press; 1994. pp. 25–55.
    3. Gouverneur V, Greedy B. Chem. Eur. J. 2002;8:767. - PubMed
    4. Sun H, DiMagno SG. J. Am. Chem. Soc. 2005;127:2050. - PubMed

    1. For examples, see: Balz G, Schiemann G. Ber. Dtsch. Chem. Ges. 1927;60:1186. Sun H, DiMagno SG. Angew. Chem. Int. Ed. 2006;45:2720..

    1. Grushin VV. Chem. Eur. J. 2002;8:1006. and references therein. - PubMed
    1. Roy AH, Hartwig JF. J. Am. Chem. Soc. 2001;123:1232. - PubMed
    2. Roy AH, Hartwig JF. J. Am. Chem. Soc. 2003;125:13944. - PubMed

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