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Review
. 2009 Jul;45(7):551-4.
doi: 10.1016/j.oraloncology.2009.01.002. Epub 2009 Feb 28.

Osteonecrosis of the jaws in patients treated with intravenous bisphosphonates (BRONJ): A concise update

Jose Bagan  1 , Crispian Scully, Vicente Sabater, Yolanda Jimenez
Affiliations
Review

Osteonecrosis of the jaws in patients treated with intravenous bisphosphonates (BRONJ): A concise update

Jose Bagan et al. Oral Oncol. 2009 Jul.

Abstract

Bisphosphonate-related osteonecrosis of the jaws (BRONJ) is a severe complication seen most frequently in patients on intravenous bisphosphonates treatment for malignant diseases. High potency bisphosphonates are generally implicated and risk factors also include dental extractions. Prevention is of paramount importance. Management is controversial but there is little evidence basis and the consensus is to be conservative. Recent advances in this area are summarised in this concise review.

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