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Comment
. 2009 Mar;9(3):211-2.
doi: 10.1016/j.cmet.2009.02.004.

Iron sensing as a partnership: HFE and transferrin receptor 2

Robert E Fleming  1
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Free article
Comment

Iron sensing as a partnership: HFE and transferrin receptor 2

Robert E Fleming. Cell Metab. 2009 Mar.
Free article

Abstract

The mechanism by which HFE participates in the regulation of iron homeostasis has remained enigmatic. Gao et al. (2009) make the key discovery that the regulation of hepcidin in response to holotransferrin requires the interaction between HFE and transferrin receptor 2 (TfR2).

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