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Comparative Study
. 2009 May;54(5):964-71.
doi: 10.1007/s10620-009-0742-3. Epub 2009 Mar 3.

Prevalence of complicated gastroesophageal reflux disease and Barrett's esophagus among racial groups in a multi-center consortium

Amy Wang  1 , Nora C Mattek, Jennifer L Holub, David A Lieberman, Glenn M Eisen
Affiliations
Comparative Study

Prevalence of complicated gastroesophageal reflux disease and Barrett's esophagus among racial groups in a multi-center consortium

Amy Wang et al. Dig Dis Sci. 2009 May.

Abstract

Aims: The Clinical Outcomes Research Initiative database was used to evaluate ethnic trends in complicated reflux disease and suspected Barrett's esophagus among various racial groups.

Methods: Endoscopic findings for procedures performed January 2000-December 2005 for any indication and for reflux-related indications were reviewed by racial group.

Results: Of 280,075 procedures examined, Hispanics were the most likely to have esophagitis (Hispanic 19.6%, white 17.3%, black 15.8%, Asian/Pacific Islander 9.5%, P-value<0.0001), and white subjects were most likely to have suspected BE (white 5.0%, Hispanic 2.9%, Asian/Pacific Islander 1.8%, black 1.5%, P-value<0.0001). Endoscopies performed for reflux-related indications had similar trends for esophagitis and esophageal stricture. Among reflux/Barrett's screening procedures adjusted for age and gender, Hispanics were most likely to have esophagitis (OR=1.28, P-value<0.0001) compared to Caucasians.

Conclusion: Our results demonstrate an association of suspected Barrett's esophagus and stricture with white patients and esophagitis with Hispanic patients. These findings need to be followed-up with further study.

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Figures

Figure 1
Figure 1
Prevalence of findings among patients undergoing upper endoscopy for dyspepsia
Figure 2
Figure 2
Prevalence of findings among patients undergoing upper endoscopy for reflux symptoms
Figure 3
Figure 3
Prevalence of findings among patients undergoing upper endoscopy for BE screening
See this image and copyright information in PMC

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