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Review
. 2008:24:89-103.
doi: 10.1016/j.yadr.2008.09.010.

Application of angiogenesis to clinical dermatology

Levi E Fried  1 , Jack L Arbiser
Affiliations
Review

Application of angiogenesis to clinical dermatology

Levi E Fried et al. Adv Dermatol. 2008.
No abstract available

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Figures

Figure 1
Figure 1. Angiogenesis in Psoriasis
Lymphocytes act to release TNF-a, IL-23 and IL-22 which induced hyperplasia in basal keratinocytes. This causes the release of VEGF, Ang2, IL-15 and IL-17 into the dermis which causes inflammation.
Figure 2
Figure 2. Pathways of different Vascular Diseases
Vascular diseases such as Malformations and lesions have differing pathways which lead to the creation of lumens of varying size.
See this image and copyright information in PMC

References

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    1. Fischer C, Jonckx B, Mazzone M, Zacchigna S, Loges S, Pattarini L, Chorianopoulos E, Liesenborghs L, Koch M, De MM, Autiero M, Wyns S, Plaisance S, Moons L, van RN, Giacca M, Stassen JM, Dewerchin M, Collen D, Carmeliet P. Anti-PlGF inhibits growth of VEGF(R)-inhibitor-resistant tumors without affecting healthy vessels. Cell. 2007;131:463–475. - PubMed
    1. Arbiser JL. Angiogenesis and the skin: a primer. J Am Acad Dermatol. 1996;34:486–497. - PubMed
    1. Arbiser JL, Karalis K, Viswanathan A, Koike C, nand-Apte B, Flynn E, Zetter B, Majzoub JA. Corticotropin-releasing hormone stimulates angiogenesis and epithelial tumor growth in the skin. J Invest Dermatol. 1999;113:838–842. - PubMed
    1. Arbiser JL, Fine JD, Murrell D, Paller A, Connors S, Keough K, Marsh E, Folkman J. Basic fibroblast growth factor: a missing link between collagen VII, increased collagenase, and squamous cell carcinoma in recessive dystrophic epidermolysis bullosa. Mol Med. 1998;4:191–195. - PMC - PubMed

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