Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2009 May;48(5):475-82.
doi: 10.1093/rheumatology/kep026. Epub 2009 Mar 3.

Infection and vasculitis

Cristina C Belizna  1 , Mohamed A Hamidou, Hervé Levesque, Loic Guillevin, Yehuda Shoenfeld
Affiliations
Review

Infection and vasculitis

Cristina C Belizna et al. Rheumatology (Oxford). 2009 May.

Abstract

Vasculitis may be associated with infection, immunization or anti-microbial drugs. Infections are responsible for a number of different types of vasculitis. Conversely, patients with vasculitis may develop infections, which sometimes mimic relapse. The aim of this review is to summarize the various aspects of the inter-relationship between vasculitis and infection, and the physiopathological mechanisms involved, in light of our current knowledge from animal models. Currently, a causal relationship between infection and vasculitis has only been established in a few instances and many mechanisms remain hypothetical. This inter-relationship is further assessed from the point of view of clinical presentation and therapeutic options, based on case reports and prospective observational data.

PubMed Disclaimer

References

    1. Pleister A, Eckels DD. Cryptic infection and autoimmunity. Autoimmun Rev. 2003;2:126–32. - PubMed
    1. Huugen D, Xiao H, van Esch A. Aggravation of anti-myeloperoxidase antibody-induced glomerulonephritis by bacterial lipopolysaccharide: role of tumor necrosis factor-alpha. Am J Pathol. 2005;167:47–58. - PMC - PubMed
    1. Buonocore S, Flamand V, Claessen N, Heeringa P, Goldman M, Florquin S. Dendritic cells overexpressing Fas-ligand induce pulmonary vasculitis in mice. Clin Exp Immunol. 2004;137:74–80. - PMC - PubMed
    1. Mathieson PW, Qasim FJ, Esnault VL, Oliveira DB. Animal models of systemic vasculitis. J Autoimmun. 1993;6:251–64. - PubMed
    1. Yamaguchi N, Macdonald DW. Detection of Aleutian disease antibodies in feral American mink in southern England. Vet Rec. 2001;149:485–8. - PubMed