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Randomized Controlled Trial
. 2009 Sep;92(3):1009-1011.
doi: 10.1016/j.fertnstert.2009.01.112. Epub 2009 Mar 3.

Intrauterine insemination with or without mild ovarian stimulation in couples with male subfertility due to oligo/astheno- and/or teratozoospermia or antisperm antibodies: a prospective cross-over trial

Felice Francavilla  1 , Filomena Sciarretta  2 , Sara Sorgentone  2 , Stefano Necozione  3 , Riccardo Santucci  2 , Arcangelo Barbonetti  2 , Sandro Francavilla  2
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Free article
Randomized Controlled Trial

Intrauterine insemination with or without mild ovarian stimulation in couples with male subfertility due to oligo/astheno- and/or teratozoospermia or antisperm antibodies: a prospective cross-over trial

Felice Francavilla et al. Fertil Steril. 2009 Sep.
Free article

Abstract

Seventy-three couples with male subfertility, which was due to oligo/astheno- and/or teratozoospermia (n = 63) or antisperm antibodies (n = 10), were randomly assigned to sequential timed natural intercourse, intrauterine insemination (IUI) and IUI + mild ovarian hyperstimulation. From the analysis of 384 observed cycles, IUI was shown to be effective in oligo/asthenozoospermia without severe teratozoospermia, when it was associated with moderate multifollicular induction, and in male immunologic subfertility, IUI was highly effective in nonstimulated cycles also.

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