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Case Reports
. 2009 Mar;5(3):171-4.
doi: 10.1038/ncpneuro1043.

Fatal Epstein-Barr virus encephalitis in a 12-year-old child: an underappreciated neurological complication?

Ariane Biebl  1 , Christine Webersinke, Bernadette Traxler, Brigitte Povysil, Dieter Furthner, Klaus Schmitt, Serge Weis
Affiliations
Case Reports

Fatal Epstein-Barr virus encephalitis in a 12-year-old child: an underappreciated neurological complication?

Ariane Biebl et al. Nat Clin Pract Neurol. 2009 Mar.

Abstract

Background: A 12-year-old boy presented to a community hospital with fever, malaise and fatigue. A polymerase chain reaction test of the cerebrospinal fluid was positive for Epstein-Barr virus. Despite intensive care treatment and antiviral drugs, the patient died 1 month after his initial presentation.

Investigations: Physical examination, polymerase chain reaction analysis of the cerebrospinal fluid, brain MRI, immunohistochemistry and molecular biological investigations of postmortem brain samples.

Diagnosis: Epstein-Barr Virus encephalitis.

Management: Aciclovir, intensive care treatment with intubation, sedation, antiepileptic drugs.

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