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Case Reports
. 2009 Feb;24(1):158-61.
doi: 10.3346/jkms.2009.24.1.158. Epub 2009 Feb 28.

A case of Graves' disease combined with hantaan virus infection

Heung Yong Jin  1 , Seon Mee Kang, So Young Kim, Ji Hyun Park, Hong Sun Baek, Tae Sun Park
Affiliations
Case Reports

A case of Graves' disease combined with hantaan virus infection

Heung Yong Jin et al. J Korean Med Sci. 2009 Feb.

Abstract

Graves' disease (GD) is generally presented by thyrotoxicosis with hyperthyroidism, and it is an organ-specific autoimmune disease induced by thyroid-stimulating hormone receptor autoantibodies. However, among diverse etiologies, viral infections have been suggested to trigger or to be involved in the pathogenesis of GD. Hantaan virus infection causing hemorrhagic fever with renal syndrome (HFRS) is common in South Korea and its pathogenesis is suggested to be an immunologic mechanism. We have experienced a patient who was diagnosed as HFRS with thyrotoxicosis. So we herein report the case as GD combined with the hantaan virus infection.

Keywords: Graves' Disease; Hantaan Virus; Hemorrhagic Fever with Renal Syndrome.

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Figures

Fig. 1
Fig. 1
Thyroid ultrasonography using 7.5 MHz probe and 99m-Tc (technecium) thyroid scan of the patient. (A) The anteroposterior diameter of the isthmus was increased to 6 mm. (B) The right lobe showed heterogenic echogenecity with increased vascularity and enlarged size. (C) The left lobe showed thyroid inferno and both lobes showed the same findings. (D) Both lobes showed increased trapping without a nodular region.
Fig. 2
Fig. 2
Vital signs during hospitalization. (A) Body temperature change. (B) Systolic (Sys) and diastolic (Dia) blood pressure (BP) and heart rate (HR) changes. (C) Urine output change.
See this image and copyright information in PMC

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