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. 2009 Mar;122(3):207-214.e4.
doi: 10.1016/j.amjmed.2008.09.034.

Risk factors for type 2 diabetes among women with gestational diabetes: a systematic review

Kesha Baptiste-Roberts  1 , Bethany B Barone, Tiffany L Gary, Sherita H Golden, Lisa M Wilson, Eric B Bass, Wanda K Nicholson
Affiliations

Risk factors for type 2 diabetes among women with gestational diabetes: a systematic review

Kesha Baptiste-Roberts et al. Am J Med. 2009 Mar.

Abstract

We conducted a systematic review of studies examining risk factors for the development of type 2 diabetes among women with previous gestational diabetes. Our search strategy yielded 14 articles that evaluated 9 categories of risk factors of type 2 diabetes in women with gestational diabetes: anthropometry, pregnancy-related factors, postpartum factors, parity, family history of type 2 diabetes, maternal lifestyle factors, sociodemographics, oral contraceptive use, and physiologic factors. The studies provided evidence that the risk of type 2 diabetes was significantly higher in women having increased anthropometric characteristics with relative measures of association ranging from 0.8 to 8.7 and women who used insulin during pregnancy with relative measures of association ranging between 2.8 and 4.7. A later gestational age at diagnosis of gestational diabetes, >24 weeks gestation on average, was associated with a reduction in risk of development of type 2 diabetes with relative measures of association ranging between 0.35 and 0.99. We concluded that there is substantial evidence for 3 risk factors associated with the risk of type 2 diabetes in women having gestational diabetes.

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Figures

Figure 1.
Figure 1.. Summary of reported measures of association between measures of anthropometry and the risk of developing type 2 diabetes following a pregnancy with gestational diabetes mellitus
* Comparison is between the highest and the lowest quartile.BMI = body mass index; kg = kilograms; m = meters; OR = odds ratio; PIBW = percent of ideal body weight; Q = quartile; RH = relative hazard; RR = relative risk
Figure 2.
Figure 2.. Summary of reported measures of association between gestational age at diagnosis of gestational diabetes mellitus and the risk of developing type 2 diabetes following a pregnancy with gestational diabetes mellitus
OR = odds ratio; Q = quartile; RH = relative hazard; RR = relative risk
Figure 3.
Figure 3.. Summary of reported measures of association between method of glucose control and the risk of developing type 2 diabetes following a pregnancy with gestational diabetes mellitus
OR = odds ratio; RH = relative hazard; RR = relative risk
See this image and copyright information in PMC

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