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. 1977 Feb;37(1):79-90.

Induction of melanogenesis in the epidermal melanoblasts of newborn mouse skin by MSH

  • PMID: 192826

Induction of melanogenesis in the epidermal melanoblasts of newborn mouse skin by MSH

T Hirobe et al. J Embryol Exp Morphol. 1977 Feb.

Abstract

The number of melanocytes positive to the dopa reaction in the epidermis was shown to increase after newborn mice were injected with alpha-MSH or DBc-AMP. The agents seemed to induce the initiation of melanogenesis in the pre-existing melanoblasts. Electron-microscopic observation also demonstrated that alpha-MSH induced not only maturation of melanosomes but also the formation of melanosomes.

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