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. 2009 Feb 7:(5):538-40.
doi: 10.1039/b819819e. Epub 2008 Dec 11.

Towards quorum-quenching catalytic antibodies

Prashant B Kapadnis  1 , Evan Hall, Madeleine Ramstedt, Warren R J D Galloway, Martin Welch, David R Spring
Affiliations

Towards quorum-quenching catalytic antibodies

Prashant B Kapadnis et al. Chem Commun (Camb). .

Abstract

The development of a novel method to attenuate bacterial virulence is reported, which is based upon the use of designed transition-state analogues to select human catalytic antibodies capable of degrading bacterial quorum-sensing molecules.

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