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. 2009 Mar;39(3):637-40.
doi: 10.1002/eji.200839050.

Human Th17 cells: are they different from murine Th17 cells?

Francesco Annunziato  1 , Lorenzo Cosmi, Francesco Liotta, Enrico Maggi, Sergio Romagnani
Affiliations
Free article

Human Th17 cells: are they different from murine Th17 cells?

Francesco Annunziato et al. Eur J Immunol. 2009 Mar.
Free article

Abstract

Type 17 Th (Th17) cells have been identified as a distinct population of CD4(+) effector T cells different from Th1 and Th2 cells. While the pre-eminent cytokine of Th1 cells is IFN-gamma and that of Th2 cells is IL-4, the distinctive cytokine of Th17 cells is IL-17A. However, although murine and human Th1 and Th2 cells exhibit strong similarities, human and murine Th17 cells seem to differ in several aspects.

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