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. 2009 Aug;83(2):139-48.
doi: 10.1111/j.1600-0609.2009.01250.x. Epub 2009 Mar 5.

Health related quality of life in a nationally representative sample of haematological patients

Anna T Johnsen  1 , Dorte Tholstrup, Morten Aa Petersen, Lise Pedersen, Mogens Groenvold
Affiliations
Free PMC article

Health related quality of life in a nationally representative sample of haematological patients

Anna T Johnsen et al. Eur J Haematol. 2009 Aug.
Free PMC article

Abstract

Objectives: Knowledge of health related quality of life of haematological patients is limited. This study aimed at investigating the prevalence and predictors of symptoms and problems in a representative sample of haematological patients in Denmark.

Methods: A random sample of patients with leukaemia, multiple myeloma and advanced lymphoma (n = 732) received the European Organisation for Research and Treatment of Cancer quality-of-life questionnaire (EORTC QLQ-C30). Mean scores were calculated. In addition, scores were dichotomised using two thresholds: patients reporting at least 'a little' of each EORTC QLQ-C30 symptom/problem were classified as having a 'symptom/problem', and patients reporting at least 'quite a bit' were classified as having a 'severe symptom/problem'. Multiple logistic regression was used to identify predictors.

Results: In total, 470 (64%) patients participated. The most frequent symptoms/problems were fatigue (55%; severe 20%), reduced role function (49%; severe 23%), insomnia (46%; severe 15%), and pain (37%; severe 15%). Older patients and patients in active antineoplastic treatment had more symptoms and problems. There was only little evidence of social inequalities.

Conclusion: This is probably the first nationally representative study of symptoms and problems in haematological patients. These patients have symptoms/problems that deserve attention. Health related quality of life is an important issue in haematological malignancies.

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Figures

Figure 1
Figure 1
Illustration of definition of ‘symptom/problem’ and ‘severe symptom/problem’.
Figure 2
Figure 2
Inclusion of patients.
See this image and copyright information in PMC

References

    1. Clemmensen I, Nedergaard KH, Storm HH. [Cancer in Denmark] [in Danish] Copenhagen: The Danish Cancer Society, FADL's Press; 2006.
    1. Fagerstrom L. The patient’s perceived caring needs as a message of suffering. J Adv Nurs. 1998;28:978–87. - PubMed
    1. Foot G, Sanson-Fisher R. Measuring the unmet needs of people living with cancer. Can Forum. 1995;19:131–5.
    1. Zittoun R. Quality of life in hematological malignancies with brief reference to bone marrow transplantation. Leuk Res. 1993;17:727–31. - PubMed
    1. Lim JW, Zebrack B. Social networks and quality of life for long-term survivors of leukemia and lymphoma. Support Care Cancer. 2006;14:185–92. - PubMed

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