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Review
. 2009 Sep;65(3):257-67.
doi: 10.1016/j.lungcan.2009.02.007. Epub 2009 Mar 13.

Stage IIIA-N2 NSCLC: a review of its treatment approaches and future developments

Jan P van Meerbeeck  1 , Veerle F M Surmont
Affiliations
Review

Stage IIIA-N2 NSCLC: a review of its treatment approaches and future developments

Jan P van Meerbeeck et al. Lung Cancer. 2009 Sep.

Abstract

Few issues are as controversial in non-small cell lung cancer as the management of patients with stage IIIA-N2 non-small cell lung cancer. This manuscript reviews the reasons and the biases inherent to this controversy and discusses the different treatment approaches with emphasis on survival as evidenced by meta-analyses and large randomised clinical trials. Prospects on novel treatment modalities and future research opportunities are presented.

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