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Review
. 2009 Apr;7(4):287-96.
doi: 10.1038/nrmicro2122.

Application of 'next-generation' sequencing technologies to microbial genetics

Daniel MacLean  1 , Jonathan D G Jones, David J Studholme
Affiliations
Review

Application of 'next-generation' sequencing technologies to microbial genetics

Daniel MacLean et al. Nat Rev Microbiol. 2009 Apr.

Abstract

New sequencing methods generate data that can allow the assembly of microbial genome sequences in days. With such revolutionary advances in technology come new challenges in methodologies and informatics. In this article, we review the capabilities of high-throughput sequencing technologies and discuss the many options for getting useful information from the data.

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