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. 2009 Jul;39(7):1047-52.
doi: 10.1007/s10803-009-0717-4. Epub 2009 Mar 17.

Prenatal stress and risk of febrile seizures in children: a nationwide longitudinal study in Denmark

Jiong Li  1 , Jørn Olsen, Carsten Obel, Jakob Christensen, Dorthe Hansen Precht, Mogens Vestergaard
Affiliations
Free PMC article

Prenatal stress and risk of febrile seizures in children: a nationwide longitudinal study in Denmark

Jiong Li et al. J Autism Dev Disord. 2009 Jul.
Free PMC article

Abstract

We aimed to examine whether exposure to prenatal stress following maternal bereavement is associated with an increased risk of febrile seizures. In a longitudinal population-based cohort study, we followed 1,431,175 children born in Denmark. A total of 34,777 children were born to women who lost a close relative during pregnancy or within 1 year before the pregnancy and they were included in the exposed group. The exposed children had a risk of febrile seizures similar to that of the unexposed children (hazard ratio (HR) 1.00, 95% CI 0.94-1.06). The HRs did not differ according to the nature or timing of bereavement. Our data do not suggest any causal link between exposure to prenatal stress and febrile seizures in childhood.

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