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Comparative Study
. 1991 Jun;35(6):1235-8.
doi: 10.1128/AAC.35.6.1235.

In vitro susceptibility testing procedures for fosfomycin tromethamine

A L Barry  1 , P C Fuchs
Affiliations
Comparative Study

In vitro susceptibility testing procedures for fosfomycin tromethamine

A L Barry et al. Antimicrob Agents Chemother. 1991 Jun.

Abstract

Fosfomycin tromethamine (previously fosfomycin trometamol) is an orally administered fosfomycin which may be used for single-dose therapy of uncomplicated urinary tract infections. Fosfomycin tromethamine, norfloxacin, and trimethoprim-sulfamethoxazole inhibited greater than 90% of 352 bacterial isolates representing 25 different species; trimethoprim and nalidixic acid had narrower spectrums of activity. Strains of Escherichia, Citrobacter, Enterobacter, and Klebsiella species were much more susceptible when glucose-6-phosphate was added to the test medium, but isolates belonging to other genera were not affected.

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References

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