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. 2009 Apr 16;11(8):1713-6.
doi: 10.1021/ol900282m.

Haliclonin A, a new macrocyclic diamide from the sponge Haliclona sp

Kyoung Hwa Jang  1 , Gyoung Won Kang, Ju-Eun Jeon, Chaemin Lim, Hyi-Seung Lee, Chung J Sim, Ki-Bong Oh, Jongheon Shin
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Haliclonin A, a new macrocyclic diamide from the sponge Haliclona sp

Kyoung Hwa Jang et al. Org Lett. .

Abstract

Haliclonin A (1), a macrocyclic diamide of a novel skeletal class, was isolated from the marine sponge Haliclona sp. collected from Korean waters. The structure of this compound was determined using a combination of spectroscopic and chemical analyses. The new compound exhibited moderate cytotoxicity and antibacterial activity against diverse microbial strains.

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