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Comparative Study
. 2009 May;47(5):1543-5.
doi: 10.1128/JCM.02134-08. Epub 2009 Mar 18.

Impact of discrepancies between the Abbott realtime and cobas TaqMan assays for quantification of human immunodeficiency virus type 1 group M non-B subtypes

M Wirden  1 , R Tubiana, F Marguet, I Leroy, A Simon, M Bonmarchand, Z Ait-Arkoub, R Murphy, A G Marcelin, C Katlama, V Calvez
Affiliations
Comparative Study

Impact of discrepancies between the Abbott realtime and cobas TaqMan assays for quantification of human immunodeficiency virus type 1 group M non-B subtypes

M Wirden et al. J Clin Microbiol. 2009 May.

Abstract

Viral loads in 249 clinical samples from individual patients infected with human immunodeficiency virus type 1 non-B subtypes were determined with both the Abbott RealTime and Cobas TaqMan assays. The differences exceeded 0.5 log for about 20% of samples and 1 log for 3%, with higher values always from the Abbott assay in the latter cases.

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Figures

FIG. 1.
FIG. 1.
Correlation curves and Bland-Altman analyses comparing the VL values obtained with the ABB assay and the CTM assay. (a and c) Data for the patients infected with a CRF02 subtype (n = 113). (b and d) Data for the patients infected with other HIV-1 group M non-B subtypes (n = 136).
See this image and copyright information in PMC

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