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. 2009 May;47(5):1568-71.
doi: 10.1128/JCM.02040-08. Epub 2009 Mar 18.

Cholera outbreaks caused by an altered Vibrio cholerae O1 El Tor biotype strain producing classical cholera toxin B in Vietnam in 2007 to 2008

Binh Minh Nguyen  1 , Je Hee Lee, Ngo Tuan Cuong, Seon Young Choi, Nguyen Tran Hien, Dang Duc Anh, Hye Ri Lee, M Ansaruzzaman, Hubert P Endtz, Jongsik Chun, Anna Lena Lopez, Cecil Czerkinsky, John D Clemens, Dong Wook Kim
Affiliations

Cholera outbreaks caused by an altered Vibrio cholerae O1 El Tor biotype strain producing classical cholera toxin B in Vietnam in 2007 to 2008

Binh Minh Nguyen et al. J Clin Microbiol. 2009 May.

Abstract

Vibrio cholerae O1 isolates collected during cholera outbreaks occurring from late 2007 to early 2008 in northern Vietnam were revealed to represent an altered strain containing the RS1 element followed by a CTX prophage harboring El Tor type rstR and classical ctxB on the large chromosome.

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Figures

FIG. 1.
FIG. 1.
Genetic map of the CTX prophage and RS1 element in V. cholerae O1 strains. For comparison, the CTX prophage and the RS1 element on each chromosome of the El Tor reference strain N16961 (6), the classical biotype reference strain O395 (3), the Mozambican strain B33 (8), and the presumed genetic map of Vietnamese strain are shown. Locations of primers and the sequenced regions with GenBank accession numbers are shown on the map of the Vietnamese strain. Black triangles represents the CTX phage integration site. Superscript terms cla and ET refer to the classical and El Tor type genes, respectively. TLC, toxin-linked cryptic plasmid.
See this image and copyright information in PMC

References

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