Polycomb repression under the skin
- PMID: 19303840
- DOI: 10.1016/j.cell.2009.03.004
Polycomb repression under the skin
Abstract
Polycomb group proteins control a hierarchy of gene expression during the differentiation of stem cells. In this issue, Ezhkova et al. (2009) show that repression mediated by Polycomb proteins controls the timing of differentiation of precursor cells of the epidermal lineage.
Comment on
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Ezh2 orchestrates gene expression for the stepwise differentiation of tissue-specific stem cells.Cell. 2009 Mar 20;136(6):1122-35. doi: 10.1016/j.cell.2008.12.043. Cell. 2009. PMID: 19303854 Free PMC article.
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