A gate keeper for axonal transport
- PMID: 19303842
- DOI: 10.1016/j.cell.2009.03.003
A gate keeper for axonal transport
Abstract
The axon and dendritic arbor of neurons require different sets of membrane proteins to carry out their functions. In this issue, Song et al. (2009) describe how a cytoplasmic diffusion barrier in the axon initial segment of rat hippocampal neurons ensures that only axonal (and not dendritic) membrane proteins enter the axon.
Comment on
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A selective filter for cytoplasmic transport at the axon initial segment.Cell. 2009 Mar 20;136(6):1148-60. doi: 10.1016/j.cell.2009.01.016. Epub 2009 Mar 5. Cell. 2009. PMID: 19268344
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