Carbapenem-resistant Acinetobacter baumannii producing OXA-23 in Thailand
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Carbapenem-resistant Acinetobacter baumannii producing OXA-23 in Thailand
Jpn J Infect Dis.
2009 Mar.
Abstract
We investigated the resistance determinant of 13 clinical isolates of carbapenem-resistant Acinetobacter baumannii collected from a regional hospital in the north of Thailand. All isolates were multidrug resistant and produced the OXA-23 carbapenemase. The bla(OXA-23) gene was found adjacent to ISAba1. Furthermore, two isolates carried the metallo beta-lactamase gene, bla(IMP). The bla(OXA-23) and bla(IMP) genes were plasmid-mediated according to the transformation assays. This is the first description of OXA-23-producing A. baumannii from Thailand.
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