Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2009 Jul;80(5):283-5.
doi: 10.1016/j.fitote.2009.03.005. Epub 2009 Mar 21.

A new dicoumarin and anticoagulant activity from Viola yedoensis Makino

Hai Yan Zhou  1 , Jun Li Hong, Pan Shu, Yue Juan Ni, Min Jian Qin
Affiliations

A new dicoumarin and anticoagulant activity from Viola yedoensis Makino

Hai Yan Zhou et al. Fitoterapia. 2009 Jul.

Abstract

A new dicoumarin, named as dimeresculetin (1), together with another dicoumarin, euphorbetin (2) and esculetin (3) were isolated from the ethyl acetate extract of the dried whole plants of Viola yedoensis Makino. The structure of 1 was elucidated as 7-hydroxy-6-[(6,7-dihydroxy-2-oxo-2H-1-benzopyran-5-yl)oxy]-2H-1-benzopyran-2-one on the basis of extensive NMR, as well as the other spectral analysis. Compounds 1-3 exhibited anticoagulant activities with respect to activated partial thromboplastin time (APTT), prothrombin time (PT) and thrombin time (TT).

PubMed Disclaimer

MeSH terms

LinkOut - more resources