The analgesic efficacy of flurbiprofen compared to acetaminophen with codeine
- PMID: 1930699
The analgesic efficacy of flurbiprofen compared to acetaminophen with codeine
Abstract
In a single-dose, parallel group, randomized block treatment allocation study, the relative analgesic efficacy of flurbiprofen, a nonsteroidal antiinflammatory drug, was compared to acetaminophen 650 mg with codeine 60 mg, zomepirac sodium 100 mg, and placebo. A total of 226 post-surgical dental patients (146 females and 80 males) participated in the study. Flurbiprofen in 50 mg and 100 mg dosages demonstrated effective analgesic activity with the 100 mg dosage being at least as effective as the acetaminophen/codeine combination. The results of this study support previous work on flurbiprofen.
Similar articles
-
Comparative study of flurbiprofen, zomepirac sodium, acetaminophen plus codeine, and acetaminophen for the relief of postsurgical dental pain.Am J Med. 1986 Mar 24;80(3A):50-4. doi: 10.1016/0002-9343(86)90111-7. Am J Med. 1986. PMID: 3515924 Clinical Trial.
-
Evaluation of ketorolac, ibuprofen, acetaminophen, and an acetaminophen-codeine combination in postoperative oral surgery pain.Pharmacotherapy. 1990;10(6 ( Pt 2)):94S-105S. Pharmacotherapy. 1990. PMID: 2082318 Clinical Trial.
-
Evaluation of ketorolac, aspirin, and an acetaminophen-codeine combination in postoperative oral surgery pain.Pharmacotherapy. 1990;10(6 ( Pt 2)):77S-93S. Pharmacotherapy. 1990. PMID: 2082317 Clinical Trial.
-
Pain management in dental practice: tramadol vs. codeine combinations.J Am Dent Assoc. 1999 Jul;130(7):1075-9. doi: 10.14219/jada.archive.1999.0338. J Am Dent Assoc. 1999. PMID: 10422401 Review.
-
[Paracetamol-codeine, an always actual choice for the treatment of pain].Minerva Med. 2014 Dec;105(6):501-13. Minerva Med. 2014. PMID: 25392959 Review. Italian.
Cited by
-
Using evidence from different sources: an example using paracetamol 1000 mg plus codeine 60 mg.BMC Med Res Methodol. 2001 Jan 10;1:1. doi: 10.1186/1471-2288-1-1. BMC Med Res Methodol. 2001. PMID: 11231885 Free PMC article. Review.
-
The efficacy of nonopioid analgesics for postoperative dental pain: a meta-analysis.Anesth Prog. 1997 Fall;44(4):119-26. Anesth Prog. 1997. PMID: 9481955 Free PMC article.
-
Analgesic efficacy and safety of paracetamol-codeine combinations versus paracetamol alone: a systematic review.BMJ. 1996 Aug 10;313(7053):321-5. doi: 10.1136/bmj.313.7053.321. BMJ. 1996. PMID: 8760737 Free PMC article.
-
Single dose oral paracetamol (acetaminophen) for postoperative pain in adults.Cochrane Database Syst Rev. 2008 Oct 8;2008(4):CD004602. doi: 10.1002/14651858.CD004602.pub2. Cochrane Database Syst Rev. 2008. PMID: 18843665 Free PMC article.
-
Single dose oral paracetamol (acetaminophen) with codeine for postoperative pain in adults.Cochrane Database Syst Rev. 2009 Jan 21;2009(1):CD001547. doi: 10.1002/14651858.CD001547.pub2. Cochrane Database Syst Rev. 2009. PMID: 19160199 Free PMC article.