Clinical Trial
doi: 10.1093/bja/67.4.397.
Clonidine decreases postoperative oxygen consumption in patients recovering from general anaesthesia
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- PMID: 1931396
- DOI: 10.1093/bja/67.4.397
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Clinical Trial
Clonidine decreases postoperative oxygen consumption in patients recovering from general anaesthesia
Br J Anaesth.
1991 Oct.
Free article
Abstract
Twenty ASA I patients, undergoing thyroid surgery were allocated randomly to receive at the end of surgery either an isotonic saline solution or clonidine 2 micrograms kg-1 i.v. administered over 20 min. Oxygen consumption (VO2) and carbon dioxide production (VCO2) were measured during recovery in patients breathing spontaneously with a head canopy system. Clonidine was found to attenuate the increase in VO2 and VCO2 associated with recovery from anaesthesia. The effect of clonidine was associated with a reduction in shivering. Sedative and analgesic properties of clonidine may also contribute to the reduction in metabolic demand during recovery from anaesthesia.
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