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. 1991 Aug;32(2):235-7.
doi: 10.1111/j.1365-2125.1991.tb03887.x.

Polymorphisms in oxidative drug metabolism: relationship to food preference

M R Britto  1 , H E McKean, G G Bruckner, P J Wedlund
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Polymorphisms in oxidative drug metabolism: relationship to food preference

M R Britto et al. Br J Clin Pharmacol. 1991 Aug.

Abstract

To determine whether a correlation exists between polymorphisms of oxidative drug metabolism and dietary preference, 29 poor metabolizers of dextromethorphan, 18 poor metabolizers of mephenytoin and 134 extensive metabolizers of both drugs were screened for their preferences for various food items. Poor metabolizers of dextromethorphan showed a diminished stated preference for cauliflower and coconut, and poor metabolizers of mephenytoin showed a diminished stated preference for spinach and cabbage.

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