Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2009 Apr 1;131(12):4194-5.
doi: 10.1021/ja8100598.

Palladium-catalyzed intramolecular direct arylation of benzoic acids by tandem decarboxylation/C-H activation

Congyang Wang  1 , Isabel Piel, Frank Glorius
Affiliations

Palladium-catalyzed intramolecular direct arylation of benzoic acids by tandem decarboxylation/C-H activation

Congyang Wang et al. J Am Chem Soc. .

Abstract

A novel protocol for the palladium-catalyzed intramolecular direct arylation of benzoic acids is reported, which combines decarboxylation and C-H activation into one efficient process. With the optimized catalyst system of palladium trifluoroacetate, silver carbonate, and the proper solvent mixture (5% DMSO/dioxane), dibenzofuran derivatives are formed in excellent yield and selectivity.

PubMed Disclaimer

Publication types

LinkOut - more resources