Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2009 Apr;12(2):192-8.
doi: 10.1016/j.mib.2009.01.006. Epub 2009 Mar 21.

Inter-kingdom signaling: chemical language between bacteria and host

Affiliations
Review

Inter-kingdom signaling: chemical language between bacteria and host

Alline R Pacheco et al. Curr Opin Microbiol. 2009 Apr.

Abstract

Chemical communication between cells ensures coordination of behavior. In prokaryotes, this chemical communication is usually referred to as quorum sensing, while eukaryotic cells signal through hormones. In the past years, a growing number of reports have shown that bacterial quorum sensing signals, called autoinducers, signal to eukaryotic cells, mimicking hormones. Conversely, host hormones can signal to bacterial cells through converging pathways to autoinducer signaling. This inter-kingdom signaling mediates symbiotic and pathogenic relationships between bacteria, mammalian and plant hosts.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Chemical signals used in cell-to-cell communication between bacteria and host.

References

    1. Fuqua WC, Winans SC, Greenberg EP. Quorum sensing in bacteria: the LuxR-LuxI family of cell density-responsive transcriptional regulators. J Bacteriol. 1994;176:269–275. - PMC - PubMed
    1. de Kievit TR, Iglewski BH. Bacterial quorum sensing in pathogenic relationships. Infect Immun. 2000;68:4839–4849. - PMC - PubMed
    1. Hughes DT, Sperandio V. Inter-kingdom signaling: communication between bacteria and host. Nature Reviews Microbiology. 2008;6:111–120. - PMC - PubMed
    1. Nealson KH, Platt T, Hastings JW. Cellular control of the synthesis and activity of the bacterial luminescent system. J Bacteriol. 1970;104:313–322. - PMC - PubMed
    1. Engebrecht J, Nealson K, Silverman M. Bacterial bioluminescence: isolation and genetic analysis of functions from Vibrio fischeri. Cell. 1983;32:773–781. - PubMed