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. 2009 Apr;48(4):356-361.
doi: 10.1097/CHI.0b013e31819aad07.

Imaging genetics

Affiliations

Imaging genetics

Andrew J Gerber et al. J Am Acad Child Adolesc Psychiatry. 2009 Apr.
No abstract available

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Figures

FIG. 1
FIG. 1
Imaging genetics allows for the identification of how common genetic polymorphisms (e.g., 5-HTTLPR) influencing molecular processes (e.g., serotonin signaling) bias neural pathways (e.g., amygdala reactivity) mediating individual differences in complex behavioral processes (e.g., trait anxiety) related to disease risk in response to environmental adversity. (Reprinted from Trends Cogn Sci. [10:182–191] Hariri AR, Holmes A. Genetics of emotional regulation: the role of the serotonin transporter in neural function. Copyright 2006, with permission from Elsevier.)

References

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    1. Viding E, Williamson DE, Hariri AR. Developmental imaging genetics: challenges and promises for translational research. Dev Psychopathol. 2006;18:877–892. - PubMed
    1. Hariri AR, Drabant EM, Weinberger DR. Imaging genetics: perspectives from studies of genetically driven variation in serotonin function and corticolimbic affective processing. Biol Psychiatry. 2006;59:888–897. - PubMed
    1. Hariri AR, Weinberger DR. Imaging genomics. Br Med Bull. 2003;65:259–270. - PubMed
    1. Plomin R, Owen MJ, McGuffin P. The genetic basis of complex human behaviors. Science. 1994;264:1733–1739. - PubMed

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