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. 1977 May 27;196(4293):995-8.
doi: 10.1126/science.193191.

Synapse formation between two clonal cell lines

C N Christian, P G Nelson, J Peacock, M Nirenberg

Synapse formation between two clonal cell lines

C N Christian et al. Science. .

Abstract

Clonal neuroblastoma x glioma hybrid cells frequently formed synapses with clonal mouse striated muscle cells. Clonal myotubes were similar to cultured mouse embryo myotubes with respect to acetylcholine sensitivity and other membrane properties examined. However, acetylcholine sensitivity measurements indicate that acetylcholine receptors of clonal myotubes are distributed more uniformly over the cell surface than the receptors of cultured mouse embryo myotubes.

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