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. 2009 Mar 24;19(6):R234-41.
doi: 10.1016/j.cub.2009.02.015.

Binding reactions: epigenetic switches, signal transduction and cancer

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Free article

Binding reactions: epigenetic switches, signal transduction and cancer

Mark Ptashne. Curr Biol. .
Free article

Abstract

Simple binding interactions lie at the heart of disparate biological functions. Multiple negative and positive 'add-ons', often with small individual effects, make elementary systems that work, work better. Cancer illustrates various of these fundamental processes gone awry.

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