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Comparative Study
. 1991 Oct 8;1090(2):255-8.

Molecular cloning of Chinese hamster metallothionein II gene and its 5' flanking region

S H Hung  1 , C W Yu, T M Chou, P C Huang, L Y Lin
Affiliations
  • PMID: 1932120
Comparative Study

Molecular cloning of Chinese hamster metallothionein II gene and its 5' flanking region

S H Hung et al. Biochim Biophys Acta. .

Erratum in

  • Biochim Biophys Acta 1992 Feb 11;1129(3):345

Abstract

A genomic DNA clone containing Chinese hamster metallothionein II (MTII) gene and its 5' flanking region was isolated from Cd resistant Chinese hamster ovary (CHO) cells. DNA sequence analysis showed that there are three exons and two introns in the structure of the MTII gene. Further characterization of the 5' flanking region reveals the possible transcription initiation site, metal responsive element and basal-level enhancer sequence. Putatively, this is the promoter region of CHO MTII gene.

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