Spinal cord stimulation as a treatment option for intractable neuropathic cancer pain
- PMID: 19325172
- PMCID: PMC2670524
- DOI: 10.3121/cmr.2008.813
Spinal cord stimulation as a treatment option for intractable neuropathic cancer pain
Abstract
Nearly 6,750,000 people suffer moderate to severe cancer-related pain each year. Unfortunately, 10% to 15% of these patients fail to achieve acceptable pain relief with conventional management. Spinal cord stimulation (SCS) has been used with increased frequency for successful treatment of intractable cancer pain. We present two cases of intractable, refractory-to-conventional treatment cancer pain that were successfully treated with SCS. Case 1 reports a 51-year-old male with burning pain at the left groin site of inguinal metastases, post-surgical and intraoperative radiation therapy for treatment of squamous cell carcinoma of the anus. Case 2 reports a 43-year-old woman with intractable, burning, throbbing, and shooting pain, post-debulking followed by radiation of a metastatic colon carcinoma. In both cases SCS implantation provided 90% to 100% pain relief, improved functioning and sleep, and discontinuation of pain medications, sustained through 12 months.
Figures
Similar articles
-
Spinal cord stimulation in the treatment of cancer-related pain: "back to the origins".Curr Pain Headache Rep. 2012 Aug;16(4):343-9. doi: 10.1007/s11916-012-0276-9. Curr Pain Headache Rep. 2012. PMID: 22610506 Review.
-
The effects of spinal cord stimulation in neuropathic pain are sustained: a 24-month follow-up of the prospective randomized controlled multicenter trial of the effectiveness of spinal cord stimulation.Neurosurgery. 2008 Oct;63(4):762-70; discussion 770. doi: 10.1227/01.NEU.0000325731.46702.D9. Neurosurgery. 2008. PMID: 18981888 Clinical Trial.
-
Intrathecal baclofen as adjuvant therapy to enhance the effect of spinal cord stimulation in neuropathic pain: a pilot study.Eur J Pain. 2004 Aug;8(4):377-83. doi: 10.1016/j.ejpain.2003.11.002. Eur J Pain. 2004. PMID: 15207519 Clinical Trial.
-
Spinal cord stimulation to treat postthoracotomy neuralgia: non-small-cell lung cancer: a case report.Pain Manag Nurs. 2012 Mar;13(1):52-9. doi: 10.1016/j.pmn.2011.11.001. Pain Manag Nurs. 2012. PMID: 22341139 Review.
-
Spinal cord stimulation versus conventional medical management for neuropathic pain: a multicentre randomised controlled trial in patients with failed back surgery syndrome.Pain. 2007 Nov;132(1-2):179-88. doi: 10.1016/j.pain.2007.07.028. Epub 2007 Sep 12. Pain. 2007. PMID: 17845835 Clinical Trial.
Cited by
-
Spinal Cord Stimulation to Treat Unresponsive Cancer Pain: A Possible Solution in Palliative Oncological Therapy.Life (Basel). 2022 Apr 7;12(4):554. doi: 10.3390/life12040554. Life (Basel). 2022. PMID: 35455045 Free PMC article. Review.
-
Gastric electrical stimulation for abdominal pain in patients with symptoms of gastroparesis.Am Surg. 2013 May;79(5):457-64. Am Surg. 2013. PMID: 23635579 Free PMC article. Clinical Trial.
-
Spinal cord stimulation in the treatment of cancer-related pain: "back to the origins".Curr Pain Headache Rep. 2012 Aug;16(4):343-9. doi: 10.1007/s11916-012-0276-9. Curr Pain Headache Rep. 2012. PMID: 22610506 Review.
-
Intrathecal Drug Delivery and Spinal Cord Stimulation for the Treatment of Cancer Pain.Curr Pain Headache Rep. 2018 Feb 5;22(2):11. doi: 10.1007/s11916-018-0662-z. Curr Pain Headache Rep. 2018. PMID: 29404792 Review.
-
Hydromorphone for cancer pain.Cochrane Database Syst Rev. 2021 Aug 5;8(8):CD011108. doi: 10.1002/14651858.CD011108.pub3. Cochrane Database Syst Rev. 2021. PMID: 34350974 Free PMC article.
References
-
- Gralow I. Cancer pain: an update of pharmacological approaches in pain therapy. Current Opinion in Anaesthesiology 2002;15(5):555–561. - PubMed
-
- Schug SA, Zech D, Dorr U. Cancer pain management according to WHO analgesic guidelines. J Pain Symptom Manage 1990;5:27–32. - PubMed
-
- Sloan PA, Melzack R. Long-term patterns of morphine dosage and pain intensity among cancer patients. Hosp J 1999;14:35–47. - PubMed
-
- Shealy CN. Dorsal column stimulation. Surg Neurol 1977;7:192. - PubMed
-
- Melzack RA, Wall PD. Pain mechanisms: a new theory. Science 1965;150:971–979. - PubMed
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical