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. 2009 Mar;5(3):e1000221.
doi: 10.1371/journal.ppat.1000221. Epub 2009 Mar 27.

New disturbing trend in antimicrobial resistance of gram-negative pathogens

Jung Hun Lee  1 , Seok Hoon Jeong, Sun-Shin Cha, Sang Hee Lee
Affiliations

New disturbing trend in antimicrobial resistance of gram-negative pathogens

Jung Hun Lee et al. PLoS Pathog. 2009 Mar.
No abstract available

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Ribbon diagram of crystallographic structure of CMY-10 (a cESBL).
The image was rendered with PyMOL, available on the Internet (http://sourceforge.net/projects/pymol). The R2-loop is represented as red, while the Ω-loop, H-2 helix, and H-11 helix are depicted in violet, blue, and cyan, respectively. The R1 active site (central upper region) is surrounded by the Ω-loop and the R2 active site (central lower region) by the R2-loop and H-11 helix. The nucleophile (Ser65), attacking the carbonyl carbon of β-lactam ring, is present in the H-2 helix.
See this image and copyright information in PMC

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