Can local radiofrequency ablation of tumors generate systemic immunity against metastatic disease?
- PMID: 19332838
- DOI: 10.1148/radiol.2511082215
Can local radiofrequency ablation of tumors generate systemic immunity against metastatic disease?
Abstract
Radiofrequency (RF) ablation may have the potential to turn a patient's tumor into an endogenous tumor vaccine; in this context of RF ablation-triggered immune system stimulation, the report by Dromi et al demonstrates a systemic immune response after local RF ablation in a mouse model.
Comment on
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Radiofrequency ablation induces antigen-presenting cell infiltration and amplification of weak tumor-induced immunity.Radiology. 2009 Apr;251(1):58-66. doi: 10.1148/radiol.2511072175. Epub 2009 Feb 27. Radiology. 2009. PMID: 19251937 Free PMC article.
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