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. 2009 Apr;6(4):240-1.
doi: 10.1038/nmeth0409-240.

mzAPI: a new strategy for efficiently sharing mass spectrometry data

Manor Askenazi, Jignesh R Parikh, Jarrod A Marto

mzAPI: a new strategy for efficiently sharing mass spectrometry data

Manor Askenazi et al. Nat Methods. 2009 Apr.
No abstract available

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Figures

Figure 1
Figure 1. Array Scanners, Telescopes, and Mass Spectrometers: XML, HDF, or API?
(a) While biological samples provide both protein and RNA, subsequent large-scale analyses (microarray or proteomics) yield data structures that diverge with respect to typical access patterns. For example (a, top), features detected by array scanners can be exported to a tabular format, immediately suited for clustering (or other multivariate analysis). In contrast (a, bottom), LC-MS experiments for proteomics generate complex multidimensional data, where feature characterization is itself, still an active area of research. The underlying raw data is repeatedly accessed as 2-dimensional slices, reconstructed ion chromatograms (RIC) for example, and hence requires inclusion of indices in file formats designed to accommodate large-scale experimental results. (b) A similar situation exists in fields outside biomedical research, where, for example, slices taken through radio frequency data yield waterfall plots and pulse profiles which are used to characterize signals of astrophysical origin.
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References

    1. Pedrioli PG, Eng JK, Hubley R, et al. Nature biotechnology. 2004;22:1459. - PubMed
    1. Deutsch E. PROTEOMICS. 2008;8:2776. - PubMed
    1. Lin SM, Zhu L, Winter AQ, et al. Expert Rev Proteomics. 2005;2:839. - PubMed
    1. Folk M, Cheng A, McGrath RE. Astronomical Data Analysis software and Systems VIII Proceedings. 1999;172
    1. Rew R, Davis G. Computer Graphics and Applications, IEEE. 1990;10:76.

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