[Selective anxiolytic afobazole increases the content of BDNF and NGF in cultured hippocampal HT-22 line neurons]
- PMID: 19334503
[Selective anxiolytic afobazole increases the content of BDNF and NGF in cultured hippocampal HT-22 line neurons]
Abstract
Experiments on immortalized hippocampal cell culture of mice showed that afobazole increases the NGF level in a final concentration of 10(-8) M and the BDNF level in final concentrations from 10(-8) to 10(-5) M.
Similar articles
-
[Effects of afobazole on the BDNF content in brain structures of inbred mice with different phenotypes of emotional stress reaction].Eksp Klin Farmakol. 2006 May-Jun;69(3):3-6. Eksp Klin Farmakol. 2006. PMID: 16878488 Russian.
-
[Neuroreceptor mechanisms of the afobazole effect].Eksp Klin Farmakol. 2009 Jan-Feb;72(1):3-11. Eksp Klin Farmakol. 2009. PMID: 19334502 Russian.
-
[Possible role of serotonin 5-HT2 receptors in mechanism of afobazole anxiolytic action: neurochemical study of inter-line differences in mice].Eksp Klin Farmakol. 2011;74(12):3-7. Eksp Klin Farmakol. 2011. PMID: 22379873 Russian.
-
[Afobazole decreases motor side effects induced by haloperidol].Eksp Klin Farmakol. 2009 Jan-Feb;72(1):15-8. Eksp Klin Farmakol. 2009. PMID: 19334504 Russian.
-
Age-dependent time course of cerebral brain-derived neurotrophic factor, nerve growth factor, and neurotrophin-3 in APP23 transgenic mice.J Neurosci Res. 2008 Sep;86(12):2774-83. doi: 10.1002/jnr.21704. J Neurosci Res. 2008. PMID: 18438945
Cited by
-
Chaperone-Dependent Mechanisms as a Pharmacological Target for Neuroprotection.Int J Mol Sci. 2023 Jan 3;24(1):823. doi: 10.3390/ijms24010823. Int J Mol Sci. 2023. PMID: 36614266 Free PMC article. Review.
-
Biological effects of exposure to 2650 MHz electromagnetic radiation on the behavior, learning, and memory of mice.Brain Behav. 2023 Jun;13(6):e3004. doi: 10.1002/brb3.3004. Epub 2023 Apr 28. Brain Behav. 2023. PMID: 37118929 Free PMC article.
-
Targeting Sigma Receptors for the Treatment of Neurodegenerative and Neurodevelopmental Disorders.CNS Drugs. 2023 May;37(5):399-440. doi: 10.1007/s40263-023-01007-6. Epub 2023 May 11. CNS Drugs. 2023. PMID: 37166702 Free PMC article. Review.