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. 2009 Jan-Feb;72(1):46-51.

[Antimutagenic and antiteratogenic properties of afobazole]

[Article in Russian]
A D Durnev, A K Zhanataev, O V Shreder, S B Seredenin
  • PMID: 19334511

[Antimutagenic and antiteratogenic properties of afobazole]

[Article in Russian]
A D Durnev et al. Eksp Klin Farmakol. 2009 Jan-Feb.

Abstract

Experiments of mice and rats showed the ability of afobazole (1, 10, and 100 mg/kg, p.o.) upon single, 5-day combined, and 5-day preliminary administration to prevent or significantly decrease the clastogenic effects of the prooxidant agent dioxidine (100 and 300 mg/kg, i.p.) and the clastogenic and teratogenic effects of the alkylating agent cyclophosphamide (20 mg/kg, i.p.).

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