Mechanisms of cyclooxygenase-2 inhibition and cardiovascular side effects: the plot thickens

Affiliations

¹ Department of Biochemistry, Chemistry, and Pharmacology, Vanderbilt Institute of Chemical Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA. larry.marnett@vanderbilt.edu

Review

Lawrence J Marnett. Cancer Prev Res (Phila). 2009 Apr.

. 2009 Apr;2(4):288-90.

doi: 10.1158/1940-6207.CAPR-09-0033. Epub 2009 Mar 31.

¹ Department of Biochemistry, Chemistry, and Pharmacology, Vanderbilt Institute of Chemical Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA. larry.marnett@vanderbilt.edu

No abstract available

Comment on

Levels of prostaglandin E metabolite and leukotriene E(4) are increased in the urine of smokers: evidence that celecoxib shunts arachidonic acid into the 5-lipoxygenase pathway.
Duffield-Lillico AJ, Boyle JO, Zhou XK, Ghosh A, Butala GS, Subbaramaiah K, Newman RA, Morrow JD, Milne GL, Dannenberg AJ. Duffield-Lillico AJ, et al. Cancer Prev Res (Phila). 2009 Apr;2(4):322-9. doi: 10.1158/1940-6207.CAPR-09-0005. Epub 2009 Mar 31. Cancer Prev Res (Phila). 2009. PMID: 19336727 Free PMC article. Clinical Trial.