Spinal extradural hematopoiesis in adolescents with thalassemia. Report of two cases and a review of the literature
- PMID: 1933920
- DOI: 10.1007/BF00249400
Spinal extradural hematopoiesis in adolescents with thalassemia. Report of two cases and a review of the literature
Abstract
Extramedullary hematopoietic tissue occurring within the extramedullary space and causing cord compression is an unusual occurrence in childhood and adolescence, and only four cases have been reported during the first two decades of life. We had the opportunity to treat a 16-year-old girl and a 14-year-old boy with paraparesis secondary to extradural extramedullary hematopoiesis. Findings in these cases are discussed, and an attempt is made to stress once more the possibility of congenital hematopoietic rests as the origin of such hyperplastic tissue. The various modes of therapy are discussed and related literature is reviewed.
Similar articles
-
The role of radiation therapy in the management of spinal cord compression due to extramedullary haematopoiesis in thalassaemia.J Neurol Neurosurg Psychiatry. 1992 Apr;55(4):310-2. doi: 10.1136/jnnp.55.4.310. J Neurol Neurosurg Psychiatry. 1992. PMID: 1583517 Free PMC article.
-
Spinal cord compression by extramedullary hematopoietic tissue in a thalassemic patient: prompt effect of radiotherapy.Haematologica. 1989 Sep-Oct;74(5):495-8. Haematologica. 1989. PMID: 2638814
-
Combined radiotherapeutic and surgical management of a spinal cord compression by extramedullary hematopoiesis in a patient with hemoglobin E beta-thalassemia.Acta Haematol. 1994;91(3):154-7. doi: 10.1159/000204322. Acta Haematol. 1994. PMID: 8091937
-
Complete recovery from paraparesis in spinal cord compression due to extramedullary haemopoiesis in beta-thalassaemia by emergency radiation therapy.Intern Med J. 2014 Apr;44(4):409-12. doi: 10.1111/imj.12386. Intern Med J. 2014. PMID: 24754690 Review.
-
Paraplegia in a pregnant thalassemic woman due to extramedullary hematopoiesis: successful management with transfusions.Surg Neurol. 1991 Sep;36(3):210-5. doi: 10.1016/0090-3019(91)90115-p. Surg Neurol. 1991. PMID: 1876971 Review.
Cited by
-
Extramedullary hemopoiesis with undiagnosed, early myelofibrosis causing spastic compressive myelopathy: Case report and review.Indian J Orthop. 2010 Jan;44(1):98-103. doi: 10.4103/0019-5413.57281. Indian J Orthop. 2010. PMID: 20165685 Free PMC article.
-
Unusual presentation of extramedullary haematopoiesis in a young boy.BMJ Case Rep. 2019 Mar 23;12(3):e227199. doi: 10.1136/bcr-2018-227199. BMJ Case Rep. 2019. PMID: 30904883 Free PMC article.
-
Lumbosacral extradural extramedullary hematopoiesis in thalassemia major causing spinal canal stenosis.Surg Neurol Int. 2020 Oct 8;11:331. doi: 10.25259/SNI_563_2020. eCollection 2020. Surg Neurol Int. 2020. PMID: 33194265 Free PMC article.
-
Progressive spinal cord compression due to epidural extramedullary hematopoiesis in thalassemia intermedia. A case report and literature review.Neuroradiol J. 2013 Feb;26(1):111-7. doi: 10.1177/197140091302600119. Epub 2013 Jan 19. Neuroradiol J. 2013. PMID: 23859178 Free PMC article. Review.
-
Cord Compression due to Extramedullary Hematopoiesis in an Adolescent with Known Beta Thalassemia Major.J Radiol Case Rep. 2009;3(1):17-22. doi: 10.3941/jrcr.v3i1.83. Epub 2009 Jan 1. J Radiol Case Rep. 2009. PMID: 22470615 Free PMC article.
References
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical