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Case Reports
. 2009 Oct;119(2):141-4.
doi: 10.1007/s10633-009-9172-y. Epub 2009 Apr 2.

Fundus autofluorescence in cone dystrophy

Nan-Kai Wang  1 , Chai Lin Chou, Luiz H Lima, Wener Cella, Joaquin Tosi, Lawrence A Yannuzzi, Stephen H Tsang
Affiliations
Case Reports

Fundus autofluorescence in cone dystrophy

Nan-Kai Wang et al. Doc Ophthalmol. 2009 Oct.

Abstract

Purpose: To describe fundus autofluorescence (FAF) finding in a case of cone dystrophy.

Methods: Interventional case report.

Results: A 23-year-old woman presented with increasing photophobia and decreasing vision in both eyes for 2 years. Fundus examination showed several drusen-like dots. FAF revealed hyper-autofluorescence in the foveola. Electroretinogram (ERG) demonstrated a pure "cone" dystrophy.

Conclusion: Hyper-autofluorescence in the foveola is a non-specific manifestation of photoreceptor-retinal pigment epithelium dysfunction. ERG studies are essential for accurate diagnosis.

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Figures

Fig. 1
Fig. 1
Fundus photography (a right eye, b left eye) revealed some small drusen-like dots around the foveal region
Fig. 2
Fig. 2
Fundus autofluorescence imaging (a right eye, b left eye) demonstrated increased autofluorescence ring and central spots in the foveola
Fig. 3
Fig. 3
Optical coherent tomography (a right eye, b left eye) showed segmentation of photoreceptor inner segment/outer segment junction between the two arrows in the fovea and no cystic changes
Fig. 4
Fig. 4
Electroretinogram revealed nearly no detectable cone responses and normal rod responses in both eyes. Black line represents the average of all tracings, and red line denotes values of a single trace
See this image and copyright information in PMC

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